Causes of Hyperparathyroidism & Hyperparathyroidism Risk Factors
The cause of most parathyroid adenomas is not known. Hyerparathyroidism most commonly develops during ages 40 and 75, but it can occur at any age. The average age of discovery is 59. There are other factors believed to increase hyperparathyroidism risk including:
• Heredity - You are at greater risk to develop the disease if other family members had hyperparathyroidism.
Usually inherited multiple endocrine neoplasia syndromes (MEN1, MEN2a, MEN2b). These are conditions that can make tumors grow in the parathyroid glands, pituitary glands and the pancreas. The condition is also called multiple endocrine adenomatosis and Wermer's syndrome.
• Radioactive iodine therapy – if treated for thyroid cancer with radioactive iodine therapy, this could increase risk.
• Radiation treatments – this was common in the 1940s and 1950s for treatment of acne or other conditions in the head and neck area.
• Radiation exposure - from nuclear power plant accidents or other sources.